Adherence testing
In some cases it may be useful to check for adherence to the existing drug regimen, particularly when there has been no apparent response to 3 or more drugs.
This investigation should only be requested after:
- Persisting hypertension is confirmed by ABPM.
- The patient is on a 4-drug regimen, (including at least 1 diuretic).
Adherence testing is arranged through the cardiovascular risk clinic via SCI gateway referral as per guidance on Refhelp.
List of drugs that can be tested for:
|
ACE inhibitor |
Enalapril, Lisinopril, Perindopril, Quinapril, Ramipril, Trandolapril |
|
Angiotensin-Receptor blockers |
Candesartan, Irbesartan, Losartan, Olmesartan, Valsartan |
|
Calcium channel blockers |
Amlodipine, Diltiazem, Felodipine, Lacidipine, Lercanidipine, Nifedipine, Verapamil |
|
Diuretics |
Thiazide/thiazide-like: Bendroflumethiazide, Chlortalidone, Hydrochlorothiazide, Indapamide K+-sparing: Amiloride, Eplerenone, Spironolactone Loop: Furosemide, Bumetanide |
|
Beta-adrenoceptor blockers |
Atenolol, Bisoprolol, Labetalol, Metoprolol |
|
Alpha-adrenoceptor blockers |
Doxazosin |
|
Centrally-acting drugs |
Methyldopa, Minoxidil, Moxonidine |
|
Other |
Aliskiren, Hydralazine |